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Work small, think big

Sphere Bio technology eases the journey to discovery by providing instruments and consumables for single cell analysis and isolation.

Built upon our picodroplet microfluidic technology, our solutions fit seamlessly into your lab workflow — saving time and providing absolute assurance of quality and reliability. We work small so you can think big.

Learn more about our platforms
Cyto-Mine

Our Products

Leveraging our expertise in picodroplet microfluidic technology, we offer high-throughput platforms, consumables, and reagents for single cell isolation as well as analysis in biologics discovery and development, cell engineering, synthetic biology, and more. We’ve collaborated with key opinion leaders to ensure that they are robust, proven, and will fit seamlessly into your workflows. Work small, think big with us.

Picodroplets – the core of our platforms

At the heart of our platforms are picodroplets. These are tiny droplets of aqueous fluid in an oil carrier fluid (a ‘single emulsion’) or an aqueous core surrounded by an oil shell in an aqueous carrier fluid (a ‘double emulsion’). Each picodroplet is used to encapsulate a cell. The chemistry of the emulsions is carefully designed to give long-term stable, biocompatible droplets with minimal leakage of molecules from the droplet, right down to small molecules such as metabolites. This provides an ultra-miniaturized test tube, containing media, reagents, and cells, that allows large-scale experiments at the single cell level.

See how our technology works

We’re the droplet microfluidic technology company for single-cell analysis and our customers are at the center of what we do.

Our integrated,
automated platforms
increase efficiency,
delivering value.
Our unmatched
picodroplet technology
is future proof
Our platform is built upon robust evidence from key opinion leaders
Our collaboration with customers is
second to none

Knowledge Hub

Webinars
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The Potential of Microfluidics Technology in Cell and Gene Therapy WebinarWebinars

The Potential of Microfluidics Technology in Cell and Gene Therapy Webinar

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Enhancing Cell Line Development: Viability & IgG Detection WebinarWebinars

Enhancing Cell Line Development: Viability & IgG Detection Webinar

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Accelerate Cell Line Development: High-Throughput Fc Fusion Screening with Cyto-Mine® ChromaWebinars

Accelerate Cell Line Development: High-Throughput Fc Fusion Screening with Cyto-Mine® Chroma

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Meet Cyto-Mine® Chroma: the next-generation platform for functional characterization and selection of live single cellsWebinars

Meet Cyto-Mine® Chroma: the next-generation platform for functional characterization and selection of live single cells

Application Notes
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Picodroplet Re-injection: Cyto-Mine® as a flexible platform for a wide range of applicationsApplication Notes

Picodroplet Re-injection: Cyto-Mine® as a flexible platform for a wide range of applications

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Cyto-Mine® Chroma: Single cell analysis and isolation using multiplexing in picodropletsApplication Notes

Cyto-Mine® Chroma: Single cell analysis and isolation using multiplexing in picodroplets

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Cyto-Cellect® Fc Fusion: Detection of Human Fc Fusion Proteins with Cyto-Mine®Application Notes

Cyto-Cellect® Fc Fusion: Detection of Human Fc Fusion Proteins with Cyto-Mine®

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Cyto-Cellect® Mouse: Detection of Mouse IgG with Cyto-Mine® PlatformsApplication Notes

Cyto-Cellect® Mouse: Detection of Mouse IgG with Cyto-Mine® Platforms

Case Studies
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Revolutionizing Biologics Discovery: The Impact of Cyto-Mine® at KU LeuvenCase Studies

Revolutionizing Biologics Discovery: The Impact of Cyto-Mine® at KU Leuven

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Pico-Mine® – Accelerating synthetic and metabolic workflows at BiosyntiaCase Studies

Pico-Mine® – Accelerating synthetic and metabolic workflows at Biosyntia

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Streamlining cell line development at FUJIFILM Diosynth BiotechnologiesCase Studies

Streamlining cell line development at FUJIFILM Diosynth Biotechnologies

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Transforming Cell Line Development Processes with Cyto-Mine® | FUJIFILM DiosynthCase Studies

Transforming Cell Line Development Processes with Cyto-Mine® | FUJIFILM Diosynth