Skip to main content
Menu
search
0

Droplet-based microfluidics advances for single-cell analysis

case study icon

Richard Hammond in Innovations in Pharmaceutical Technology

Droplet-based microfluidics advances for single-cell analysis

Richard IPT Article 2023
PUBLISHED IN
ARTICLE TITLE
AUTHOR
PUBLICATION DATE
FEATURED EXPERT
Innovations in Pharmaceutical Technology
Droplet-based microfluidics advances for single-cell analysis
Richard Hammond
September 29, 2023
Richard Hammond, Chief Technology Officer, Sphere Bio

Droplet-based microfluidics is revolutionizing single-cell analysis by enabling rapid encapsulation, characterisation, and sorting of cells within microdroplets.

This technology offers automation, speed, and sensitivity improvements while reducing cost and maintaining cell viability, accelerating pharmaceutical and biotech research.

Richard Hammond highlights new developments such as non-fluorescent detection methods, functional co-encapsulation assays, gene editing integration, and double-emulsion droplets that broaden applications into immuno-oncology, neurobiology, and synthetic biology.

Richard Hammond

Richard Hammond, CTO

“Droplet-based microfluidics transforms single-cell analysis by combining precision, speed, and versatility, opening new frontiers in biological research and therapeutic development.”

Key Notes

tick icon

Droplet microfluidics enables high-throughput single-cell encapsulation with low shear stress, rapid screening, and minimal reagent use.

tick icon

New modalities include brightfield imaging and mass spectrometry, expanding detection beyond fluorescence.

tick icon

Functional assays and gene editing within droplets simulate complex cell interactions and improve editing efficiency.

tick icon

Double-emulsion droplets retain hydrophobic molecules, expanding biochemical analysis capabilities.

For more insights on the latest developments in biologics and cell line research, visit Sphere Bio’s Knowledge Hub or or dive into our Cyto-Mine® Chroma solution for early-stage screening.

This article is part of our Editorial Coverage series, showcasing Sphere Bio’s thought leadership and technological contributions in top-tier industry publications. Stay tuned for more.