Cyto-Mine® Chroma: Single cell analysis and isolation using Multiplexing in Picodroplets
Discover the Power of Multiplexed Screening with Cyto-Mine® Chroma
Cyto-Mine® Chroma builds on the success of Cyto-Mine® with enhanced fluorescence detection and expanded multiplexing capabilities. Now equipped with four lasers across independent colour channels, it allows for higher-resolution cellular profiling, improved assay flexibility, and deeper insights for antibody discovery and cell line development.
This new application note highlights the power of multi-laser detection, including a cell-binding assay that leverages multi-colour fluorescence to distinguish cell types and assess antibody binding—all within a single picodroplet.
What You’ll Learn in This App Note:
Multiplexing in action
See how a three-colour cell-binding assay enables precise detection of antibody-secreting cells, target cells, and antibody binding efficiency in real time.
FRET-based assays
Learn how a four-colour fluorescence resonance energy transfer (FRET) assay enhances antibody secretion detection.
Next-gen screening depth
Discover how multi-laser capabilities improve assay resolution, accuracy, and flexibility for antibody discovery and cell line development.
Key Features Demonstrated:
Multiplexed fluorescence detection
Perform high-precision multi-colour assays for deeper screening insights.
Co-encapsulation capabilities
Screen antibody-secreting cells and target cells together for more functional and relevant assays.
Optimised secretion assays
Improve sensitivity in antibody secretion detection, accelerating therapeutic discovery.
Breakthrough Assays in This Study:
- FRET secretion assay – High-sensitivity detection of IgG secretion using FRET.
- Cell-binding assay – Multi-colour profiling to analyse antibody interactions with membrane antigens.
Download the application note now.
The Next Generation: Cyto-Mine® Chroma
Automate. Accelerate. Analyze millions of cells in a single day.
Think Cyto-Mine®, but supercharged, enabling multiplexing and greater assay flexibility to fit your needs. It means that you can examine vastly greater numbers of cells — and isolate the most valuable ones— with unparalleled precision.
